The Red Devils boss has stuck with the team that got their season off to a flyer against West Ham last week – winning 4-0.
Romulu Lukaku, who scored twice on his league debut for United last week, again leads the line up front, with England starlet Marcus Rashford again out on the wing.
Swansea, meanwhile, have made two changes and a change of formation to the team that drew 0-0 with Southampton in their first game of the season.
Summer signing Roque Mesa comes into the side in place of Leon Britton in the centre of midfield, while Kyle Bartley replaced Wayne Routledge as manager Paul Clement switches his side from 4-3-3 to 5-3-2.
See the two line-ups IN FULL below:
Swansea team: Fabianski, Mawson, Fernandez, Bartley, Naughton, Roque, Fer, Carroll, Olsson, Abraham, Ayew
Subs: van der Hoorn, Narsingh, Nordfeldt, Routledge, Rangel, Fulton, McBurnie
Man United team: De Gea, Valencia, Bailly, Jones, Blind, Matic, Pogba, Mata, Mkhitaryan, Rashford, Lukaku
Subs: Lindelof, Martial, Smalling, Lingard, Romero, Ander Herrera, Fellaini
Referee: Jon Moss (W Yorkshire)